A closer look at 7-OH: Kratom’s strongest alkaloid revealed.

Every now and then, a new substance comes along that captures attention, offering an alternative to harder drugs and promising relief without the same risks.

In recent years, kratom has emerged as a go-to option for many seeking pain relief, relaxation, or a way to manage stress—especially those looking to avoid the pitfalls of opioids or prescription painkillers.

At the core of kratom’s effects is 7-OH, short for 7-hydroxy mitragynine, also abbreviated as 7OH mitragynine. 

7-OH: A Strong Component Of Kratom

7-OH is a natural compound found in small amounts (around 2%) in the kratom plant (Mitragyna speciosa).

Compared to mitragynine, the primary alkaloid in kratom, 7-OH is much stronger. 

One test-tube laboratory study found 7-OH to be 40 times more potent than mitragynine and 10x stronger than morphine in antinociceptive assays, which measure pain relief effectiveness. 

7-OH can deliver these powerful pain-relieving effects due to its ability to interact with opioid receptors in the brain. 

These receptors are responsible for controlling many of our body's functions, from pain to mood and pleasure. But, overactivation of them through drugs like opioids can lead to dangerous effects like respiratory depression, addiction, and dependence. 

Some kratom strains, especially red vein varieties, tend to have more 7-OH compared to others, which can make their effects much stronger. 

7-OH Effects – The Good & The Bad

7-OH is one of the reasons kratom is so effective—but it comes with both perks and drawbacks.

The effects of 7-OH come on quickly—many users report feeling 7-OH’s effects within 10 to 15 minutes of consumption, which has made it an appealing option for those seeking fast relief. 

In general, the effects of 7-OH may include but are not limited to:

• Pain relief through interaction with opioid receptors

• Increased feelings of relaxation

• Mood enhancement

• Increased sedation, especially at higher doses

• Reduced anxiety and feelings of stress

• Potential for tolerance buildup with frequent use

• Risk of dependence with prolonged high-dose usage

• Reduced energy levels or drowsiness in some users

Where To Buy 7-OH

Like any other product market, be it food, thc hemp fashion, or home goods, the kratom or 7-OH space offers a dizzying number of brand options. 

A quick search for “7-OH near me” or “kratom near me” will hit you with an overwhelming list of brands selling products that all seem pretty similar. 

At Modus, only the most premium leaves from the Mitragyna speciosa plant are selected to create a natural extract that then gets infused into various kratom 7-OH products.

7-OH Tablets

Modus offers 7-OH Capsules, each containing 10mg of potent kratom. These capsules deliver the typical effects of 7-OH—elevated mood, a sense of calm relaxation, and relief from physical discomfort.

For a stronger experience, try the 7-OH Tablets, available in a 1-count and 4-count with 20mg of extract per tablet. Choose from Mint, Blue Razz, Mixed Berry, or Natural flavors.

A quick heads-up: Many Reddit users mention that Modus products tend to hit harder than other brands, so it’s wise to start slow and gauge your tolerance.

7-OH Shots

For those with higher tolerance levels, Modus’ 7-OH Shots pack a powerful punch with 30mg of high-potency kratom per bottle. These shots are made using carefully selected kratom leaves, which are cured, fermented, and nanotized to extract the most beneficial alkaloids.

Be cautious—drinking the entire shot in one go can lead to very strong effects, so start with a smaller dose to avoid overdoing it.

7-OH Gummies 

For a tastier way to enjoy kratom, Modus offers 7-OH Gummies, each infused with 10mg of kratom that works just as quickly as the shots or tablets. 

Available at $24.99 per 5-pack. 

Conclusion: 7-OH Is Strong With Desirable Effects

Kratom is pretty fascinating. Certain studies have pointed out that its second most active compound, 7-OH, is roughly 40x stronger than mitragynine—delivering a highly concentrated extract with plenty of favorable effects.

From general mood enhancement to targeted pain relief, 7-OH has a unique ability to interact with opioid receptors in the brain. Although safe, sourcing from trusted vendors like Modus ensures a more controlled, enjoyable experience.

Whether you're considering kratom for relief, relaxation, or general wellness, 7-OH is here to help. Start low and go slow, as proper dosing and responsible use are essential.

Zachary Walls

Born and raised in Northern California to a family with generations of cannabis knowledge. In addition to being a cannabis connoisseur himself, Zach is an owner/operator at a popular barbershop in the East Bay. In his spare time, Zach creates music and has worked with many influential bay area hip-hop and r&b artists. Follow on Instagram.